Helping early-stage teams know what their programs need next

In mountaineering, an alpine start means launching before dawn. Every decision is made the night before. The climber who hesitates, over-packs, or waits for perfect conditions does not summit.

Biotech works the same way.

The founders who succeed are not just running great science. They are moving in parallel. While the biology is being validated, they are thinking about patient stratification, CMC strategies, and regulatory expectations.

Founded by Gene Petrella, Alpine Start Bio is a biotech and drug discovery advisory firm that helps pre-seed to pre-Series A biotech teams make the right calls early. We bring deep cross-functional experience across discovery, translational science, regulatory strategy, and clinical development so teams can move with confidence at every stage.

We bring downstream thinking forward to keep the program on the path to clinic.